Dealing with Active Ingredient Degradation in Aerosols

Dealing with Active Ingredient Degradation in Aerosols

Step-by-Step Guide to Prevent Active Ingredient Degradation

What Is Active Ingredient Degradation?

Degradation of active ingredients in aerosol formulations occurs due to chemical reactions, temperature changes, or prolonged exposure to air or light. This compromises product efficacy and shelf life.

Steps to Prevent Degradation

Step 1: Use Stabilizers

Incorporate stabilizers or preservatives into the formulation to protect active ingredients from oxidation and breakdown.

Step 2: Choose Protective Packaging

Opt for aerosol can designs with UV-blocking properties and airtight seals to minimize exposure to harmful elements.

Step 3: Control Storage Conditions

Store products in a cool, dry environment to reduce degradation risks. Avoid exposure to direct sunlight or fluctuating temperatures.

Pharma Tip:  Preventing Nozzle Blockages During Aerosol Production

Step 4: Conduct Regular Testing

Perform periodic stability testing to monitor the integrity of active ingredients over time.

Conclusion

Preventing active ingredient degradation involves using stabilizers, protective packaging, and optimal storage practices. These measures ensure the long-term efficacy and quality of aerosol products.